Our latest data highlight, entitled: Large effort study to elucidate replication initiation in bacteria, is based on Knöppel et al. (2023).

Over the last 50 years, the research community has studied the coordination of DNA copying and cell division in bacteria. The studies completed have shown that a protein called DnaA is key in the replication of Escherichia coli. Recent studies have made use of microscropy in order to advance our understanding of E. coli replication processes, but much is still unknown. Knöppel et al. used high-throughput fluorescence microscopy to study the coordination of replction and division cycles in E. coli. Their results supported the initiator activation/deactivation cycling model for E. coli replication initiation, but the researchers advocate for further studies into this model.

Read more in the Data Highlight: Large effort study to elucidate replication initiation in bacteria. You’ll also see other highlights on related topics at the bottom of the article.

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